Diamond-Lipid Hybrids Enhance Chemotherapeutic Tolerance and Mediate Tumor Regression
نویسندگان
چکیده
منابع مشابه
Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.
Cross-linking agents that induce DNA interstrand cross-links (ICL) are widely used in anticancer chemotherapy. Yeast genetic studies show that nucleotide excision repair (NER), Rad6/Rad18-dependent postreplication repair, homologous recombination, and cell cycle checkpoint pathway are involved in ICL repair. To study the contribution of DNA damage response pathways in tolerance to cross-linking...
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ژورنال
عنوان ژورنال: Advanced Materials
سال: 2013
ISSN: 0935-9648
DOI: 10.1002/adma.201300343